Ac-FLTD-CMK
Ac-FLTD-CMK is an inhibitor derived from abscisicin D (GSDMDD) with specific inhibitory effects on inflammatory caspases. ac-FLTD-CMK showed inhibitory effects on caspases-1, caspases-4 and caspases-11 with IC50s of 46.7 nM, 1.49 μM and 329 nM, respectively. Ac-FLTD-CMK showed potency against caspases-1, caspases-4 and caspases-11, but not against apoptosis-associated caspase-3.
Product Specifications
CAS Number
2376255-48-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
569.05
Molecular Formula
C26H37ClN4O8
Notes
Research use only, not for human use.
Receptor
Caspase
Available Sizes
Curated Selection
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