Isodeoxycholic Acid
Isodeoxycholic Acid is a bile acid that is formed via epimerization of deoxycholic acid by intestinal bacteria. It has a greater critical micelle concentration than DCA, indicating reduced detergent activity, and is less active than DCA in inhibiting growth in a panel of seven gut commensal bacteria species. Isodeoxycholic Acid (0.1%) inhibits spore germination induced by taurocholic acid in several C. difficile strains, as well as decreases the cytotoxicity of C. difficile culture supernatants to Vero cells. Plasma levels of isodeoxycholic acid are decreased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet.
Product Specifications
CAS Number
566-17-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
392.57
Molecular Formula
C24H40O4
Notes
Research use only, not for human use.
Receptor
Antibacterial | Chloride channel
Available Sizes
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