IL-4-inhibitor-1
IL-4 inhibitor is an inhibitor of IL-4.1It binds to IL-4 with a Kdvalue of 1.8 μM and inhibits IL-4 activity in a cell-based reporter assay (EC50= 1.81 μM) . It is selective for IL-4 over IL-13 (EC50= 18.2 μM) . IL-4 inhibitor inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes (EC50= 3.1 μM), indicating inhibition of the IL-4-JAK1-STAT6 signaling pathway.
Product Specifications
CAS Number
1332184-63-0
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
321.31
Molecular Formula
C18H12FN3O2
Notes
Research use only, not for human use.
Receptor
IL Receptor
Available Sizes
Curated Selection
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