PRGL493
PRGL493 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4) .1It inhibits formation of arachidonoyl-CoA (AA-CoA) from arachidonic acid in, as well as the proliferation and migration of, PC3 and MDA-MB-231 cancer cells when used at a concentration of 50 μM. PRGL493 (5 μM) reduces production of progesterone induced by 8-Br-cyclic AMP (8-Br-cAMP) in MA-10 Leydig tumor cells. It inhibits tumor growth in a PC3 mouse xenograft model when administered at a dose of 0.25 mg/kg.
Product Specifications
CAS Number
2479378-45-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
451.48
Molecular Formula
C25H21N7O2
Notes
Research use only, not for human use.
Receptor
Others
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6335764-01 0.2 mL
POLR2J, CT (POLR2J, POLR2J1, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit J-1, RNA polymerase II 13.3kD subunit) (APC)
Sign In for Pricing
View Details MBS6335764-02 5x 0.2 mL
POLR2J, CT (POLR2J, POLR2J1, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit J-1, RNA polymerase II 13.3kD subunit) (APC)
Sign In for Pricing
View Details 
CRB1000263-01 0.5 mg
BCL-6 corepressor Human (BCOR) (498-514) C-terminal Biotin
Sign In for Pricing
View Details CRB1000263-02 1 mg
BCL-6 corepressor Human (BCOR) (498-514) C-terminal Biotin
Sign In for Pricing
View Details