PRGL493
PRGL493 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4) .1It inhibits formation of arachidonoyl-CoA (AA-CoA) from arachidonic acid in, as well as the proliferation and migration of, PC3 and MDA-MB-231 cancer cells when used at a concentration of 50 μM. PRGL493 (5 μM) reduces production of progesterone induced by 8-Br-cyclic AMP (8-Br-cAMP) in MA-10 Leydig tumor cells. It inhibits tumor growth in a PC3 mouse xenograft model when administered at a dose of 0.25 mg/kg.
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
451.48
Molecular Formula
C25H21N7O2
Notes
Research use only, not for human use.
Receptor
Others
CAS Number
2479378-45-3
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
RC204243L2V 200 µL
Tcl1 (TCL1A) (NM_021966) Human Tagged ORF Clone Lentiviral Particle
Ask
View Details 
