Mitoguazone
Mitoguazone (Methyl-GAG) is a selective S-adenosyl-methionine decarboxylase inhibitor that penetrates the blood-brain barrier and disrupts polyamine biosynthesis. Mitoguazone is a synthetic polycarbonyl derivative with anti-tumor activity that inhibits the integration of HIV DNA into cellular DNA in monocytes and macrophages, inducing apoptosis. Mitoguazone can be used to prevent acute leukemia, Hodgkin lymphoma and non-Hodgkin lymphoma.
Product Specifications
CAS Number
459-86-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
184.2
Molecular Formula
C5H12N8
Notes
Research use only, not for human use.
Receptor
Apoptosis | HIV Protease
Available Sizes
Curated Selection
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