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TL12-186

TL12-186 is a Cereblon-dependent kinase degrader that degrades CDK, BTK, FLT3, Aurora and other kinases.TL12-186 inhibits CDK2/cyclin A and CDK9/cyclin T1 with IC50s of 73 and 55 nM, respectively.

Product Specifications

CAS Number

2250025-88-6

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

931.46

Molecular Formula

C44H51ClN10O9S

Notes

Research use only, not for human use.

Receptor

PROTACs | CDK

Available Sizes

Frequently Asked Questions

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