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TAS-119

TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95 nM.TAS-119 has a higher affinity for Aurora A than for Aurora B.TAS-119 exhibits potent antitumor activity and potential antimitotic activity. TAS-119 has potent anti-tumor activity and potential anti-mitotic activity.

Product Specifications

CAS Number

1453099-83-6

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

506.36

Molecular Formula

C23H22Cl2FN5O3

Notes

Research use only, not for human use.

Receptor

Aurora Kinase

Available Sizes

Frequently Asked Questions

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