TAS-119
TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95 nM.TAS-119 has a higher affinity for Aurora A than for Aurora B.TAS-119 exhibits potent antitumor activity and potential antimitotic activity. TAS-119 has potent anti-tumor activity and potential anti-mitotic activity.
Product Specifications
CAS Number
1453099-83-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
506.36
Molecular Formula
C23H22Cl2FN5O3
Notes
Research use only, not for human use.
Receptor
Aurora Kinase
Available Sizes
Frequently Asked Questions
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