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ZLD1039

ZLD1039 is a potent, orally bioavailable EZH2 (Enhancer of Zeste Homolog 2) inhibitor with high selectivity. It demonstrates strong, concentration-dependent inhibition of both wild-type and mutant (Y641F and A677G) PRC2 (Polycomb Repressive Complex 2) enzymatic activities, exhibiting IC50 values of 5.6, 15, and 4.0 nM, respectively. Additionally, ZLD1039 effectively suppresses breast tumor growth and metastasis.

Product Specifications

CAS Number

1826865-46-6

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

612.8

Molecular Formula

C36H48N6O3

Notes

Research use only, not for human use.

Receptor

Histone Methyltransferase

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