ZLD1039
ZLD1039 is a potent, orally bioavailable EZH2 (Enhancer of Zeste Homolog 2) inhibitor with high selectivity. It demonstrates strong, concentration-dependent inhibition of both wild-type and mutant (Y641F and A677G) PRC2 (Polycomb Repressive Complex 2) enzymatic activities, exhibiting IC50 values of 5.6, 15, and 4.0 nM, respectively. Additionally, ZLD1039 effectively suppresses breast tumor growth and metastasis.
Product Specifications
CAS Number
1826865-46-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
612.8
Molecular Formula
C36H48N6O3
Notes
Research use only, not for human use.
Receptor
Histone Methyltransferase
Available Sizes
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