Upacicalcet
Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-sensitive receptors, thereby lowering blood levels of PTH.Upacicalcet is an orthosteric modulator of calcium-sensitive receptors and prevents adenine-induced secondary vascular calcification and bone disease in a rat model of adenine-induced secondary hyperparathyroidism.
Product Specifications
CAS Number
1333218-50-0
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
351.76
Molecular Formula
C11H14ClN3O6S
Notes
Research use only, not for human use.
Receptor
Calcium Channel
Available Sizes
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