Ticolubant

Ticolubant is orally active leukotriene B4 antagonist with high affinity for the human neutrophil LTB4 receptor (Ki = 0.78 nM), blocks LTB4-induced Ca2+ migration with an IC50 of 6.6 ± 1.5 nM, and shows topical anti-inflammatory activity in a mouse model of skin inflammation.

Product Specifications

CAS Number

154413-61-3

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

460.37

Molecular Formula

C23H19Cl2NO3S

Notes

Research use only, not for human use.

Receptor

Calcium Channel | LTR

Available Sizes

Curated Selection

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