Ticolubant
Ticolubant is orally active leukotriene B4 antagonist with high affinity for the human neutrophil LTB4 receptor (Ki = 0.78 nM), blocks LTB4-induced Ca2+ migration with an IC50 of 6.6 ± 1.5 nM, and shows topical anti-inflammatory activity in a mouse model of skin inflammation.
Product Specifications
CAS Number
154413-61-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
460.37
Molecular Formula
C23H19Cl2NO3S
Notes
Research use only, not for human use.
Receptor
Calcium Channel | LTR
Available Sizes
Curated Selection
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