Tenofovir exalidex
Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant HIV strains, including those resistant to multiple nucleoside/nucleotide analogs. It effectively inhibits all major HIV-1 and HIV-2 subtypes in fresh human PBMCs, as well as all evaluated HIV-1 strains in monocyte-derived macrophages, displaying EC50 values between 0.2 and 7.2 nM. Oral administration of CMX157 shows no apparent toxicity. Additionally, Tenofovir exalidex exhibits antiviral properties against HBV.
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
569.72
Molecular Formula
C28H52N5O5P
Notes
Research use only, not for human use.
Receptor
Antiviral
CAS Number
911208-73-6
Available Sizes
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