CCR2 antagonist 5
CCR2 antagonist 5 (JNJ-41443532) is a selective and orally active hCCR2 inhibitor with good binding affinity (IC50=37 nM) and potent functional antagonism (chemotaxis IC50=30 nM) .JNJ-41443532 binds mCCR2 with a Ki of 9.6 µM, which can be used to study inflammatory diseases and diabetes. diseases and diabetes.
Product Specifications
CAS Number
1228650-83-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
482.52
Molecular Formula
C22H25F3N4O3S
Notes
Research use only, not for human use.
Receptor
CCR
Available Sizes
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