GSK1733953A
GSK1733953A can be used as a small molecule Mycobacterium tuberculosis respiration inhibitor with an inhibitory effect on MenG activity and an IC50 value of 2.6 ± 0.6 μM.GSK1733953A is a selective biphenylbenzamide with an inhibitory effect on the catalytic methylation of the Mycobacterium tuberculosis desmethylnaphthoquinone methyltransferase, and the MIC of GSK1733953A against Mycobacterium tuberculosis H4Rv was 8.37 μg/ml. MIC of 8.37 μg/ml and MIC of 1.2 to 9.6 μg/ml against drug-resistant strains.GSK1733953A is a candidate compound for the treatment of tuberculosis.
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
385.82
Molecular Formula
C21H17ClFNO3
Notes
Research use only, not for human use.
Receptor
Antibacterial
CAS Number
930470-97-6
Available Sizes
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