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BMS 182874

BMS 182874 is an orally effective and highly selective endothelin receptor ETA antagonist with an IC50 value of 0.150 μM for ETA and a Ki value of 0.055 μM for ETA.BMS 182874 is able to reduce arterial pressure in a rat hypertension model induced by Deoxycorticosterone acetate. BMS 182874 was able to reduce Deoxycorticosterone-induced arterial pressure in a rat model of hypertension and can be used to study cardiovascular disease.

Product Specifications

CAS Number

153042-42-3

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

345.42

Molecular Formula

C17H19N3O3S

Notes

Research use only, not for human use.

Receptor

Endothelin Receptor

Available Sizes

Frequently Asked Questions

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