BMS 182874
BMS 182874 is an orally effective and highly selective endothelin receptor ETA antagonist with an IC50 value of 0.150 μM for ETA and a Ki value of 0.055 μM for ETA.BMS 182874 is able to reduce arterial pressure in a rat hypertension model induced by Deoxycorticosterone acetate. BMS 182874 was able to reduce Deoxycorticosterone-induced arterial pressure in a rat model of hypertension and can be used to study cardiovascular disease.
Product Specifications
CAS Number
153042-42-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
345.42
Molecular Formula
C17H19N3O3S
Notes
Research use only, not for human use.
Receptor
Endothelin Receptor
Available Sizes
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