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AK301

AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM) . Colon cancer cells arrested in mitosis with AK301 readily underwent a p53-dependent apoptosis following compound withdrawal and arrest release.

Product Specifications

CAS Number

314022-97-4

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

344.84

Molecular Formula

C19H21ClN2O2

Notes

Research use only, not for human use.

Receptor

Microtubule Associated | Apoptosis

Available Sizes

Curated Selection

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