SP-100030
SP-100030 is a dual inhibitor of NF-κB and activator protein-1 (AP-1), demonstrating potent inhibition with IC50 values of 50 nM for both. It effectively reduces the production of IL-2, IL-8, and TNF-alpha in Jurkat and other T cell lines. Additionally, SP-100030 has been shown to decrease the severity of murine collagen-induced arthritis (CIA) .
Product Specifications
CAS Number
154563-54-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
437.65
Molecular Formula
C14H5ClF9N3O
Notes
Research use only, not for human use.
Receptor
NF-κB
Available Sizes
Curated Selection
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