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SKA-111

SKA-111 is a selective calcium-activated potassium phannel (potassium phannel) KCa3.1 activator that induces membrane hyperpolarization in porcine endothelial cells.SKA-111 binds to the interface between the CaM N-valve and the S4-S5 junction and ameliorates Bradykinin-induced dilation of coronary arteries in the isolated rat heart, which can be used for the study of cardiovascular diseases. study of cardiovascular diseases.

Product Specifications

CAS Number

1369170-24-0

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

214.29

Molecular Formula

C12H10N2S

Notes

Research use only, not for human use.

Receptor

Potassium Channel

Available Sizes

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