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Hh-Ag1.5

Hh-Ag1.5 (SAG-1.5) is a potent Hedgehog (Hh) agonist (EC50: 1 nM) and Smoothened (Smo) receptor agonist, with an EC50 of 1 nM and Ki values between 0.5 and 2.3 nM for Smo. Hh-Ag1.5-mediated reprogramming breaks the quiescent state of non-injured hepatic stem cells and thus rescues liver failure. Hh-Ag1.5 induced differentiation of hiPSCs into skin precursor cells, spinal motor neurons and spinal sensory neurons.

Product Specifications

CAS Number

612542-14-0

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

526.04

Molecular Formula

C28H26ClF2N3OS

Notes

Research use only, not for human use.

Receptor

Hedgehog/Smoothened

Available Sizes

Curated Selection

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