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Inflachromene

Inflachromene (ICM) is an inhibitor of HMGB1 and HMGB expression with anti-inflammatory activity.Inflachromene reduces seizure severity in a mouse model of epilepsy by inhibiting HMGB1 translocation, inhibits endothelial proliferation through the HMGB1/2-regulated TLR4-NF-κB pathway, and inhibits autophagy by regulating Beclin 1 activity. Inflachromene can be used to study epilepsy.

Product Specifications

CAS Number

908568-01-4

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

377.39

Molecular Formula

C21H19N3O4

Notes

Research use only, not for human use.

Receptor

Others

Available Sizes

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