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Y134

Y134 is an estrogen receptor inhibitor that is selective and orally active, exhibiting strong antagonist activity against ERα and Erβ with Ki of 0.09 nM and 11.31 nM, respectively. The selectivity of Y134 for ERα is 121.1 times higher than that for ERβ. Y134 inhibited the proliferation of ER positive human breast cancer cells stimulated by estrogen.

Product Specifications

CAS Number

849662-80-2

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

472.6

Molecular Formula

C28H28N2O3S

Notes

Research use only, not for human use.

Receptor

Estrogen Receptor/ERR

Available Sizes

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