LE135
LE135 is a potent RAR antagonist that binds selectively to RARα (Ki of 1.4 μM) and RARβ (Ki of 220 nM), showing higher affinity for RARβ. It is highly selective over RARγ, RXRα, RXRβ, and RXRγ. LE135 also acts as a potent TRPV1 and TRPA1 receptor activator with EC50s of 2.5 μM and 20 μM, respectively.
Product Specifications
CAS Number
155877-83-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
438.56
Molecular Formula
C29H30N2O2
Notes
Research use only, not for human use.
Receptor
Retinoid Receptor
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog