MEG hemisulfate
MEG hemisulfate (Mercaptoethylguanidine hemisulfate) acts as a highly potent and selective suppressor of inducible NO synthase (iNOS), demonstrating EC50 values of 11.5 μM for iNOS, 110 μM for ecNOS, and 60 μM for bNOS in tissue homogenates. It is notably effective as a peroxynitrite scavenger and blocks peroxynitrite-triggered oxidative mechanisms. Furthermore, this compound offers protective benefits across various experimental inflammation prototypes, such as ischemia/reperfusion injury, hemorrhagic shock, periodontitis, inflammatory bowel disease, and both endotoxic and septic shock.
Product Specifications
CAS Number
3979-00-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
336.44
Molecular Formula
C6H20N6O4S3
Notes
Research use only, not for human use.
Receptor
NOS
Available Sizes
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