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IWP-3

IWP-3 is a potent inhibitor of Wnt production with an IC50 of 40 nM. It inhibits Porcupine (Porcn), blocking the palmitoylation of Wnt proteins, and moderately inhibits CK1γ3 and CK1ε, but does not inhibit CK1α .

Product Specifications

CAS Number

687561-60-0

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

484.59

Molecular Formula

C22H17FN4O2S3

Notes

Research use only, not for human use.

Receptor

Wnt/beta-catenin

Available Sizes

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