IWP-3
IWP-3 is a potent inhibitor of Wnt production with an IC50 of 40 nM. It inhibits Porcupine (Porcn), blocking the palmitoylation of Wnt proteins, and moderately inhibits CK1γ3 and CK1ε, but does not inhibit CK1α .
Product Specifications
CAS Number
687561-60-0
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
484.59
Molecular Formula
C22H17FN4O2S3
Notes
Research use only, not for human use.
Receptor
Wnt/beta-catenin
Available Sizes
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