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PF-4981517

PF-4981517 (CYP3cide) is a efficient, specific and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4) . The IC 50 values for CYP3A activity are 0.03 μM,17 μM, and 71 μM for CYP3A4, CYP3A5, and CYP3A7, respectively. PF-4981517 is able to be used to distinguish the contributions of CYP3A4 versus CYP3A5 on drug Metabolism.

Product Specifications

CAS Number

1390637-82-7

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

456.59

Molecular Formula

C26H32N8

Notes

Research use only, not for human use.

Receptor

P450

Available Sizes

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