TAK-441

TAK-441 is an orally active inhibitor of Hedgehog signaling (IC50 = 4.4 nM) with potent antitumor activity. TAK-441 suppresses transcription factor Gli1 mRNA expression and tumor growth.

Product Specifications

CAS Number

1186231-83-3

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

576.56

Molecular Formula

C28H31F3N4O6

Notes

Research use only, not for human use.

Receptor

Hedgehog/Smoothened

Available Sizes

Curated Selection

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