TAK-441
TAK-441 is an orally active inhibitor of Hedgehog signaling (IC50 = 4.4 nM) with potent antitumor activity. TAK-441 suppresses transcription factor Gli1 mRNA expression and tumor growth.
Product Specifications
CAS Number
1186231-83-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
576.56
Molecular Formula
C28H31F3N4O6
Notes
Research use only, not for human use.
Receptor
Hedgehog/Smoothened
Available Sizes
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