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Oxatomide

Oxatomide (Oxatomida) is a potent and orally active dual H1 histamine receptor and P2X7 receptor antagonist with antihistamine and antiallergic activity.Oxatomide can be used to block ATP-induced currents in the human P2X7 receptor with an IC50 value of 0.95 μM.Oxatomide has an inhibitory effect on ATP-induced Ca2+ inward currents with an IC50 value of 0.43 μM.Oxatomide inhibits 5-hydroxytryptamine. Oxatomide inhibits 5-hydroxytryptamine with an IC50 of 0.43 μM.Oxatomide is used in the treatment of immune system diseases and in the study of hypersensitivity reactions.

Product Specifications

CAS Number

60607-34-3

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

426.55

Molecular Formula

C27H30N4O

Notes

Research use only, not for human use.

Receptor

5-HT Receptor | Calcium Channel | P2X Receptor | Histamine Receptor

Available Sizes

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