Tefinostat
Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor that is cleaved to the active acid CHR-2847 by intracellular esterase human carboxylesterase-1 (hCE-1) . Tefinostat exhibits antitumor activity and can be used in the study of leukemia and advanced hematologic malignancies.
Product Specifications
CAS Number
914382-60-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
495.61
Molecular Formula
C28H37N3O5
Notes
Research use only, not for human use.
Receptor
HDAC
Available Sizes
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