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Tefinostat

Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor that is cleaved to the active acid CHR-2847 by intracellular esterase human carboxylesterase-1 (hCE-1) . Tefinostat exhibits antitumor activity and can be used in the study of leukemia and advanced hematologic malignancies.

Product Specifications

CAS Number

914382-60-8

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

495.61

Molecular Formula

C28H37N3O5

Notes

Research use only, not for human use.

Receptor

HDAC

Available Sizes

Frequently Asked Questions

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