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Calyculin A

Calyculin A ((-) -Calyculin A), a toxicant in the Japanese marine sponge CDiscodermia calyxC, is a selective and potent inhibitor of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A), inducing hyperactivation of cryopreserved bovine spermatozoa and inhibiting radiation-induced gammaH2AX DNA repair disease in human lymphocytes. gammaH2AX DNA repair foci in human lymphocytes.

Product Specifications

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

1009.17

Molecular Formula

C50H81N4O15P

Notes

Research use only, not for human use.

Receptor

Phosphatase

CAS Number

101932-71-2

Available Sizes

Curated Selection

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