Barbadin
Barbadin is a novel and specific inhibitor of β-arrestin/β2-adaptin interaction with an IC50 value of 19.1 μM for β-arestin1 and 15.6 μM for β-arestin2. Barbadin potentiates the long term effects of lorcaserin on POMC neurons and weight loss. Barbadin potentiates the long-term effects of lorcaserin on POMC neurons and weight loss, blocks agonist-promoted endocytosis of prototypic β2-adrenergic, V2-vasopressin, and angiotensin-II-1 receptors, and may be useful in the study of obesity.
Product Specifications
CAS Number
356568-70-2
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
333.41
Molecular Formula
C19H15N3OS
Notes
Research use only, not for human use.
Receptor
Arrestin
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![[ (3aR,4R,6Z,10Z,11aR) -6,10-Dimethyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] (E) -4-acetyloxy-2- (hydroxyme thyl) but-2-enoate](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
JEA77086-01 10 mg
[ (3aR,4R,6Z,10Z,11aR) -6,10-Dimethyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] (E) -4-acetyloxy-2- (hydroxyme thyl) but-2-enoate
Sign In for Pricing
View Details JEA77086-02 25 mg
[ (3aR,4R,6Z,10Z,11aR) -6,10-Dimethyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] (E) -4-acetyloxy-2- (hydroxyme thyl) but-2-enoate
Sign In for Pricing
View Details JEA77086-03 50 mg
[ (3aR,4R,6Z,10Z,11aR) -6,10-Dimethyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] (E) -4-acetyloxy-2- (hydroxyme thyl) but-2-enoate
Sign In for Pricing
View Details 
