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Atabecestat

Atabecestat (JNJ-54861911) is a potent, brain-penetrant, and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor that achieves robust and high CSF Aβ reduction, is well-tolerated, and displays sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer's Disease treatment.

Product Specifications

CAS Number

1200493-78-2

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

367.4

Molecular Formula

C18H14FN5OS

Notes

Research use only, not for human use.

Receptor

BACE

Available Sizes

Curated Selection

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