Atabecestat
Atabecestat (JNJ-54861911) is a potent, brain-penetrant, and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor that achieves robust and high CSF Aβ reduction, is well-tolerated, and displays sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer's Disease treatment.
Product Specifications
CAS Number
1200493-78-2
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
367.4
Molecular Formula
C18H14FN5OS
Notes
Research use only, not for human use.
Receptor
BACE
Available Sizes
Curated Selection
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