Apricitabine
Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase α, β and γ with Ki values of 300 μM, 12 μM and 112.25 μM, respectively. Apricitabine has shown good antiretroviral therapeutic efficacy in antiretroviral HIV-infected patients, with good tolerability and low selective resistance.
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
229.26
Molecular Formula
C8H11N3O3S
Notes
Research use only, not for human use.
Receptor
DNA/RNA Synthesis | HIV Protease
CAS Number
160707-69-7
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6295561-01 0.1 mL
ENC1, CT (ENC1, KLHL37, NRPB, PIG10, Ectoderm-neural cortex protein 1, Kelch-like protein 37, Nuclear matrix protein NRP/B, p53-induced gene 10 protein) (MaxLight 405)
Ask
View Details MBS6295561-02 5x 0.1 mL
ENC1, CT (ENC1, KLHL37, NRPB, PIG10, Ectoderm-neural cortex protein 1, Kelch-like protein 37, Nuclear matrix protein NRP/B, p53-induced gene 10 protein) (MaxLight 405)
Ask
View Details 
MBS7205878-01 48 Well
Chicken BTB/POZ domain-containing protein KCTD5 (KCTD5) ELISA Kit
Ask
View Details