Aphidicolin
Aphidicolin, an antibiotic derived from the mold Cephalosporium aphidicola, is a potent inhibitor of DNA (deoxyribonucleic acid) synthesis, effectively hindering the proliferation of herpes simplex virus. It targets DNA polymerase α and δ, disrupting mitotic cell division by affecting DNA polymerase activity. Additionally, aphidicolin enhances apoptosis when combined with arabinosyl nucleosides in a human promyelocytic leukemia cell line.
Product Specifications
CAS Number
38966-21-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
338.48
Molecular Formula
C20H34O4
Notes
Research use only, not for human use.
Receptor
Others
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