TCMDC-135051
TCMDC-135051 is a potent and selective PfCLK3 protein kinase inhibitor demonstrating significant antiparasiticidal activity (EC50=320 nM) while exhibiting minimal off-target toxicity. It effectively hinders the transition from trophozoite to schizont, impairs transcription, and diminishes transmission to the mosquito vector.
Product Specifications
CAS Number
2413716-15-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
471.59
Molecular Formula
C29H33N3O3
Notes
Research use only, not for human use.
Receptor
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