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Neriifolin

Neriifolin (17β-Neriifolin), a cardiac glycoside extracted from the unripe fruit of Cerbera manghas, is a Na+K+-ATPase inhibitor with anticancer activity that inhibits cell proliferation by suppressing HOXA9-dependent gene expression and inducing apoptosis in the human acute myeloid cell line, THP-1. Neriifolin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells and can be used in prostate cancer research.

Product Specifications

CAS Number

466-07-9

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

534.68

Molecular Formula

C30H46O8

Notes

Research use only, not for human use.

Receptor

Autophagy | ATPase | Apoptosis

Available Sizes

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