Ilorasertib hydrochloride
Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s: 1 nM, 7 nM, 120 nM) . It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: 7 nM, 3 nM, and 32 nM) .
Product Specifications
CAS Number
1847485-91-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
525
Molecular Formula
C25H22ClFN6O2S
Notes
Research use only, not for human use.
Receptor
Aurora Kinase
Available Sizes
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