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GSK-843

GSK-843 (GSK'843) is a selective and potent RIP3 inhibitor with an IC50 value of 8.6 nM for the structural domain of RIP3 kinase. It has potential analgesic activity, inhibits the expression of RIP3 and NLRP3 in the SDH of CFA mice, and can be used as adjunctive therapy for treating inflammation.

Product Specifications

CAS Number

1601496-05-2

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

377.49

Molecular Formula

C19H15N5S2

Notes

Research use only, not for human use.

Receptor

RIP kinase

Available Sizes

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