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VX-984 B

VX-984 (M9831) is an oral, selective DNA-PK inhibitor that can cross the blood-brain barrier. VX-984 inhibited the conjugation of non-homologous terminal NHEJ and acted on DSBs to break DNA double strand. VX-984 is commonly seen in glioblastoma (GBM) and non-small cell lung cancer (NSC-LC) studies.

Product Specifications

CAS Number

1476074-39-1

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

415.49

Molecular Formula

C23H21D2N7O

Notes

Research use only, not for human use.

Receptor

DNA-PK

Available Sizes

Frequently Asked Questions

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