VX-984 B
VX-984 (M9831) is an oral, selective DNA-PK inhibitor that can cross the blood-brain barrier. VX-984 inhibited the conjugation of non-homologous terminal NHEJ and acted on DSBs to break DNA double strand. VX-984 is commonly seen in glioblastoma (GBM) and non-small cell lung cancer (NSC-LC) studies.
Product Specifications
CAS Number
1476074-39-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
415.49
Molecular Formula
C23H21D2N7O
Notes
Research use only, not for human use.
Receptor
DNA-PK
Available Sizes
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