DB1976
DB1976 is a selenophene analog of DB270 and a highly potent, cell-permeable, fully efficacious transcription factor PU.1 inhibitor. It effectively inhibits PU.1 binding (IC50 of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-λB affinity, KD of 12 nM) in vitro. Additionally, DB1976 has an apoptosis-inducing effect.
Product Specifications
CAS Number
1557397-51-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
447.35
Molecular Formula
C20H16N8Se
Notes
Research use only, not for human use.
Receptor
Apoptosis
Available Sizes
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