AZ12601011 B
AZ12601011 is an orally active, selective and potent TGFBR1 kinase inhibitor.AZ12601011 inhibits the release of inflammatory factors, interleukin (IL) -1β, IL-6 and tumor necrosis factor-α, and inhibits the growth of breast tumors.AZ12601011 directly binds to TGF-βR1 and blocks downstream Smad3 activation, which can be used to prevent renal fibrosis.
Product Specifications
CAS Number
2748337-86-0
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
313.36
Molecular Formula
C19H15N5
Notes
Research use only, not for human use.
Receptor
ALK | TGF-beta/Smad
Available Sizes
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