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AZ12601011 B

AZ12601011 is an orally active, selective and potent TGFBR1 kinase inhibitor.AZ12601011 inhibits the release of inflammatory factors, interleukin (IL) -1β, IL-6 and tumor necrosis factor-α, and inhibits the growth of breast tumors.AZ12601011 directly binds to TGF-βR1 and blocks downstream Smad3 activation, which can be used to prevent renal fibrosis.

Product Specifications

CAS Number

2748337-86-0

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

313.36

Molecular Formula

C19H15N5

Notes

Research use only, not for human use.

Receptor

ALK | TGF-beta/Smad

Available Sizes

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