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MRTX1133

MRTX1133 is a potent, selective, noncovalent KRASG12D inhibitor. It has picomolar binding affinity, single-digit nanomolar activity in cellular assays. In addition, it has significant in vivo efficacy in tumor models harboring KRASG12D mutations.

Product Specifications

CAS Number

2621928-55-8

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

600.63

Molecular Formula

C33H31F3N6O2

Notes

Research use only, not for human use.

Receptor

——

Available Sizes

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