M62812
TLR4 inhibitor. Inhibits LPS-induced NF-κB activation in HEK293 cells (IC50 = 2.4 μg/mL) . Also inhibits LPS-induced cytokine production and procoagulant effects in PBMCs and HUVECs. Prolongs survival in a mouse septic shock model.
Product Specifications
CAS Number
613263-00-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
330.23
Molecular Formula
C13H13Cl2N3OS
Notes
Research use only, not for human use.
Receptor
——
Available Sizes
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