M62812

TLR4 inhibitor. Inhibits LPS-induced NF-κB activation in HEK293 cells (IC50 = 2.4 μg/mL) . Also inhibits LPS-induced cytokine production and procoagulant effects in PBMCs and HUVECs. Prolongs survival in a mouse septic shock model.

Product Specifications

CAS Number

613263-00-6

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

330.23

Molecular Formula

C13H13Cl2N3OS

Notes

Research use only, not for human use.

Receptor

——

Available Sizes

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