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JAK2-IN-7

JAK2-IN-7 is a selective JAK2 inhibitor with IC50s of 3, 11.7, and 41 nM for JAK2, SET-2, and Ba/F3V617F cells, respectively. JAK2-IN-7 possesses >14-fold selectivity over JAK1, JAK3, FLT3. JAK2-IN-7 stimulates cell cycle arrest in the G0/G1 phase and induces tumor cellapoptosis. Antitumor activities.

Product Specifications

CAS Number

2593402-36-7

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

459.59

Molecular Formula

C26H33N7O

Notes

Research use only, not for human use.

Receptor

——

Available Sizes

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